Kebab

The Kebab is a piercing melee weapon with 5 damage, +1 Reach, and 8 uses. The reach extension lets you attack from a tile further back than normal, and the penetration means every enemy in the line behind the primary target also takes the hit. In corridor encounters or anywhere enemies bunch up, one swing can clip two or three targets simultaneously without any extra cost.

The 8-use limit means it won't last a full run — use it aggressively during fights where enemies line up rather than saving it. Against isolated targets the piercing does nothing and the 5 damage is unexceptional, so keep a secondary weapon ready for those situations. Strong in the early and mid game; by late game its fixed damage starts falling behind.