Mewgenics Invention Quests Guide

Invention Quests are Mewgenics' sidequest system — 21 optional challenges that task your cats with completing specific goals in exchange for powerful rewards. Unlike the main quest chain, Invention Quests can be tackled in any order and persist across multiple runs, making them a key part of long-term progression.

Each quest comes with a curse — a run-long debuff that applies the moment you accept the quest. Completing the quest objective removes the curse and grants the permanent reward. If you fail the run, the curse is lifted but progress may reset, so plan accordingly.

How Invention Quests Work

Invention Quests are offered by the Inventor NPC, who appears in your base area. You can accept multiple quests at once, but each active quest stacks its curse on your current run. Experienced players often stack 2–3 manageable curses to maximize reward gain per run.

Quest objectives range from killing enemies with specific elements, using certain item types, reaching particular areas, to breeding cats with specific traits. Some objectives require multiple runs to complete — especially those involving rare trait combinations.

Rewards are permanent unlocks or persistent bonuses that carry across all future runs. Completing all 21 quests is one of the major long-term goals of the game and significantly expands what builds are available to you.

All 21 Invention Quests

1. The Spark of Life

Curse: All cats start each run with 1 HP. Objective: Survive the first 3 floors without losing a cat. Reward: Cats begin each run with +5 max HP permanently. One of the earlier quests most players complete — pair with defensive abilities and avoid tanking hits to survive the opening floors.

2. Trial by Fire

Curse: All enemies gain the Burning status at the start of combat, but so do your cats. Objective: Kill 50 enemies with Fire-element abilities. Reward: Unlocks the Pyromancer class for breeding. Lean into fire builds and take classes or abilities with fire synergy to complete this efficiently.

3. Cold Reception

Curse: Your cats move last in every combat turn regardless of speed stats. Objective: Kill 40 enemies with Ice-element abilities. Reward: Unlocks the Glacialist class. The always-last curse is brutal — use defensive setups and abilities that don't rely on going first to survive.

4. Static Discharge

Curse: Each time a cat uses an ability, there is a 20% chance it damages a random ally instead. Objective: Kill 50 enemies with Lightning-element abilities. Reward: Unlocks the Stormcaller class. The friendly-fire curse is dangerous in multi-cat parties — solo or tanky builds tolerate it better.

5. Toxic Waste

Curse: All food items are replaced with Toxic variants that poison cats when consumed. Objective: Kill 40 enemies with Poison-element abilities. Reward: Unlocks the Venomancer class. Avoid eating if you can — or build around poison immunity to negate the curse entirely.

6. Dead Weight

Curse: Cats cannot pick up items during combat. Objective: Complete a full run using only abilities (no items used in combat). Reward: Cats gain +2 to all ability damage permanently. A natural fit for ability-focused builds — if you already play without items much, this quest is low-friction.

7. Paper Cats

Curse: All cats have their max HP halved for the duration of the run. Objective: Complete 5 floors without any cat falling below 1 HP. Reward: Permanently unlocks a new defensive mutation in the mutation pool. Very hard curse — prioritize barrier/shield abilities and avoid multi-target attacks.

8. The Long Game

Curse: All enemies have double HP. Objective: Kill 100 enemies total across any number of runs. Reward: All cats deal +10% damage permanently. The doubled-HP curse makes runs longer and more resource-intensive — high-damage builds complete this fastest.

9. Blessed Offspring

Curse: Breeding produces half the normal number of kittens per litter. Objective: Breed a cat with 3 rare or higher traits. Reward: Litter size is permanently increased by 1. A direct breeding challenge — invest in genetic manipulation items and rare trait carriers to complete it.

10. Purebred

Curse: Mutated cats deal 50% less damage. Objective: Complete a run using only cats with no mutations. Reward: Non-mutated cats permanently gain +3 to all stats. Useful if you run clean cats, but the damage penalty makes the curse very difficult to survive with mutated cats in your roster.

11. Feral Instinct

Curse: Cats with disorders deal 25% reduced damage. Objective: Win a combat encounter using only cats that have at least one disorder. Reward: Disorders now sometimes provide positive side-effects in addition to negative ones. A good quest if you lean into disorder builds — the curse is a wash if you're using disordered cats anyway.

12. Glass Cannon

Curse: Cats take double damage from all sources. Objective: Deal 500 total damage in a single run. Reward: All cats permanently deal +15% damage. The double-damage curse demands burst builds and kill-before-killed tactics.

13. One Cat Army

Curse: You may only bring one cat into combat. Objective: Win 10 combat encounters with a single cat. Reward: Solo cats permanently gain a stacking damage bonus for each floor survived alone. Great for players who already favor single-cat runs.

14. Strength in Numbers

Curse: Each cat in your party reduces all cats' individual damage by 10%. Objective: Win a combat with 4 or more cats alive simultaneously. Reward: Party-wide stat bonuses scale better with party size. Counter-intuitive for the curse — run support/heal builds to keep everyone alive long enough to trigger the win condition.

15. No Pain No Gain

Curse: Healing abilities heal for half the normal amount. Objective: Heal a total of 200 HP across all cats in a single run. Reward: All healing abilities permanently heal for +20% more. The irony is real — spam healing abilities constantly to grind the 200 HP despite the halved curse.

16. Speed Demon

Curse: Enemies always go first in combat. Objective: Reach the final floor of a run in under 30 minutes. Reward: All cats permanently gain +3 Speed. A time-based challenge — play decisively, skip non-essential encounters, and use high-damage quick-kill builds.

17. Pacifist Run

Curse: Every combat encounter you skip causes all cats to lose 5 HP. Objective: Complete 3 full floors without killing any enemies (non-lethal wins or avoidance only). Reward: Unlocks a unique negotiation ability for one cat. One of the hardest quests — you must engage encounters but not kill, requiring very specific setups.

18. Genetic Perfection

Curse: Cats lose 1 stat point every time they breed. Objective: Breed a cat with max stats in two or more attributes. Reward: Stat caps are raised by 2 permanently for all cats. A long-term breeding challenge — minimize how often your best cats breed to avoid the stat drain.

19. Collector

Curse: Item drop rates are halved. Objective: Collect 10 unique items in a single run. Reward: Item shops always have one extra item for sale permanently. Requires thorough clearing of each floor — fight every encounter to maximize drops despite the reduced rate.

20. Boss Hunter

Curse: Mini-bosses appear on every floor instead of only designated floors. Objective: Defeat 5 bosses in a single run. Reward: Boss kills permanently drop one additional reward item. Ironically, the curse makes the objective easier — every floor has boss encounters now, just survive them all.

21. Legacy

Curse: Any cat that dies is permanently removed from your roster, even across runs. Objective: Complete a full run without losing a single cat. Reward: Cats that survive a full run permanently gain a unique Legacy trait. The most punishing quest in the game — save it for last, use your strongest cats, and play extremely conservatively.

General Tips

Stack curses strategically. Quests with mild curses (like Dead Weight if you already ignore items, or Feral Instinct if you run disorder builds) pair well together. Avoid stacking Glass Cannon with Paper Cats — the combined damage multiplication will kill your runs fast.

Prioritize quests whose objectives align with your preferred playstyle. If you enjoy breeding optimization, tackle the breeding quests (Blessed Offspring, Genetic Perfection, Purebred) in the same runs so your build naturally completes them.

Some quest rewards fundamentally change your available strategies. Completing The Long Game (+10% damage) and Glass Cannon (+15% damage) early makes all subsequent runs and quest attempts significantly easier.

Save Legacy (quest 21) for last. Its permanent roster permadeath curse is run-ending if you lose a valued cat — do it only once you've completed everything else and have a roster you're willing to risk.