Overview
The Destroyer is a late-game major boss with 500 HP. At this HP level the fight requires sustained combat over many rounds and demands a healer as a core party member. The name implies a damage-focused design: expect wide-area attacks, terrain destruction, or enrage mechanics that escalate damage output over time.
Strategy
Position your tank centrally to intercept frontal attacks. With a boss named The Destroyer, wide-area cleave or stomp attacks hitting multiple adjacent tiles are likely.
Apply DoT stacks early (bleed, poison) and let them drain HP passively. At 500 HP passive damage is highly efficient over the length of the fight.
Save your highest-burst ability for an enrage phase if one triggers. Enrage mechanics commonly activate at 50% or 25% HP, increasing attack speed or damage significantly. Having a major ability ready for that window can end the fight before the escalation becomes unmanageable.